MO → MO · about 98 miles
Cape Girardeau to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Cape Girardeau to St. Louis. The fastest takes 1 hour 50 minutes; every bus leaves at 9:10 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 1h 50m
- Leaves at
- 9:10 PM
Timetable
Every bus leaves from Cape Girardeau Leming Lane and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 9:10 PM | 11:00 PM | 1h 50m | Daily | Greyhound Full timetable |
Route map
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Where to board in Cape Girardeau Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Cape Girardeau
- Cape Girardeau Leming Lane Map of Cape Girardeau Leming Lane (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Cape Girardeau
Questions
How long is the bus from Cape Girardeau to St. Louis?
The fastest direct bus takes 1 hour 50 minutes.
What time is the first bus from Cape Girardeau to St. Louis?
Every departure is at 9:10 PM (Daily).
Which bus companies go from Cape Girardeau to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Cape Girardeau?
Buses to St. Louis leave from Cape Girardeau Leming Lane.