MO → TN · about 156 miles
Cape Girardeau to Memphis bus schedule
Greyhound runs 7 direct buses a week from Cape Girardeau to Memphis. The fastest takes 3 hours 15 minutes; every bus leaves at 3:15 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 3h 15m
- Leaves at
- 3:15 AM
Timetable
Every bus leaves from Cape Girardeau Leming Lane and arrives at Memphis Greyhound Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:15 AM | 6:30 AM | 3h 15m | Daily | Greyhound Full timetable |
Route map
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Where to board in Cape Girardeau Where you get off in Memphis The route of the busiest trip
Where to catch the bus in Cape Girardeau
- Cape Girardeau Leming Lane Map of Cape Girardeau Leming Lane (Google Maps)
Where the bus stops in Memphis
Return trip: Memphis to Cape Girardeau
Questions
How long is the bus from Cape Girardeau to Memphis?
The fastest direct bus takes 3 hours 15 minutes.
What time is the first bus from Cape Girardeau to Memphis?
Every departure is at 3:15 AM (Daily).
Which bus companies go from Cape Girardeau to Memphis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Cape Girardeau?
Buses to Memphis leave from Cape Girardeau Leming Lane.