MO → LA · about 510 miles
Cape Girardeau to New Orleans bus schedule
Greyhound runs 7 direct buses a week from Cape Girardeau to New Orleans. The fastest takes 14 hours 35 minutes; every bus leaves at 3:15 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 14h 35m
- Leaves at
- 3:15 AM
Timetable
Every bus leaves from Cape Girardeau Leming Lane and arrives at New Orleans Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:15 AM | 5:50 PM | 14h 35m | Daily | Greyhound Full timetable |
Route map
The map needs JavaScript.
Where to board in Cape Girardeau Where you get off in New Orleans The route of the busiest trip
Where to catch the bus in Cape Girardeau
- Cape Girardeau Leming Lane Map of Cape Girardeau Leming Lane (Google Maps)
Where the bus stops in New Orleans
- New Orleans Union Passenger Terminal Map of New Orleans Union Passenger Terminal (Google Maps)
Return trip: New Orleans to Cape Girardeau
Questions
How long is the bus from Cape Girardeau to New Orleans?
The fastest direct bus takes 14 hours 35 minutes.
What time is the first bus from Cape Girardeau to New Orleans?
Every departure is at 3:15 AM (Daily).
Which bus companies go from Cape Girardeau to New Orleans?
Greyhound runs direct buses on this route.
Where do I catch the bus in Cape Girardeau?
Buses to New Orleans leave from Cape Girardeau Leming Lane.