IL → MO · about 87 miles
Springfield to St. Louis bus & train schedule
Amtrak and FlixBus run 53 direct buses and trains a week from Springfield to St. Louis. The fastest takes 1 hour 40 minutes; the first departure leaves at 4:35 AM and the last at 10:19 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 53
- Fastest trip
- 1h 40m
- First departure
- 4:35 AM
- Last departure
- 10:19 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 4:35 AM | 6:20 AM | 1h 45m | Mon, Thu, Fri, Sat, Sun | Springfield Smtd Transfer Center to St Louis Bus Station | FlixBus Full timetable |
| 10:13 AM | 12:01 PM | 1h 48m | Daily | Springfield to St. Louis | Amtrak Full timetable |
| 12:56 PM | 2:51 PM | 1h 55m | Daily | Springfield to St. Louis | Amtrak Full timetable |
| 1:55 PM | 3:40 PM | 1h 45m | Mon, Thu, Fri, Sat, Sun | Springfield Smtd Transfer Center to St Louis Bus Station | FlixBus Full timetable |
| 5:26 PM | 7:25 PM | 1h 59m | Daily | Springfield to St. Louis | Amtrak Full timetable |
| 8:28 PM | 10:23 PM | 1h 55m | Daily | Springfield to St. Louis | Amtrak Full timetable |
| 9:40 PM | 11:20 PM | 1h 40m | Mon, Thu, Fri, Sat, Sun | Springfield Smtd Transfer Center to St Louis Bus Station | FlixBus Full timetable |
| 10:19 PM | 12:09 AM +1 day | 1h 50m | Daily | Springfield to St. Louis | Amtrak Full timetable |
Route map
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Where to board in Springfield Where you get off in St. Louis The route of the busiest trip
Where to board in Springfield
Where buses and trains stop in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Springfield
Questions
How long is the bus or train from Springfield to St. Louis?
The fastest direct bus or train takes 1 hour 40 minutes; the typical trip is 1 hour 55 minutes.
What time is the first departure from Springfield to St. Louis?
The earliest departure is at 4:35 AM (Mon, Thu, Fri, Sat, Sun) and the last at 10:19 PM (Daily).
Which bus and rail companies go from Springfield to St. Louis?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in Springfield?
Buses and trains to St. Louis leave from Springfield Amtrak station and Springfield Smtd Transfer Center.