MO → MO · about 237 miles
Kansas City to St. Louis bus & train schedule
Amtrak and Greyhound run 35 direct buses and trains a week from Kansas City to St. Louis. The fastest takes 4 hours; the first departure leaves at 4:10 AM and the last at 4:05 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 35
- Fastest trip
- 4h 00m
- First departure
- 4:10 AM
- Last departure
- 4:05 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 4:10 AM | 8:10 AM | 4h 00m | Daily | Kansas City Bus Station to St Louis Bus Station | Greyhound Full timetable |
| 6:00 AM | 12:05 PM | 6h 05m | Daily | Kansas City Bus Station to St Louis Bus Station | Greyhound Full timetable |
| 8:40 AM | 2:20 PM | 5h 40m | Daily | Kansas City to St. Louis | Amtrak Full timetable |
| 3:50 PM | 10:55 PM | 7h 05m | Daily | Kansas City Bus Station to St Louis Bus Station | Greyhound Full timetable |
| 4:05 PM | 9:45 PM | 5h 40m | Daily | Kansas City to St. Louis | Amtrak Full timetable |
Route map
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Where to board in Kansas City Where you get off in St. Louis The route of the busiest trip
Where to board in Kansas City
Where buses and trains stop in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Kansas City
Questions
How long is the bus or train from Kansas City to St. Louis?
The fastest direct bus or train takes 4 hours; the typical trip is 5 hours 40 minutes.
What time is the first departure from Kansas City to St. Louis?
The earliest departure is at 4:10 AM (Daily) and the last at 4:05 PM (Daily).
Which bus and rail companies go from Kansas City to St. Louis?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in Kansas City?
Buses and trains to St. Louis leave from Kansas City Amtrak station and Kansas City Bus Station.