MO → IA · about 182 miles

Kansas City to Des Moines bus schedule

Jefferson Lines and Greyhound run 28 direct buses a week from Kansas City to Des Moines. The fastest takes 3 hours 10 minutes; the first bus leaves at 8:35 AM and the last at 11:25 PM. The standard fare with Jefferson Lines is $40 one way.

Timetable data from · Schedule last changed

Buses a week
28
Fastest trip
3h 10m
First bus
8:35 AM
Last bus
11:25 PM
Standard fare
$40

A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Greyhound aren't listed here.

Timetable

Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.

Direct buses from Kansas City, MO to Des Moines, IA
DepartsArrivesDurationDaysStopsBus companyStandard fare & ticket
8:35 AM12:00 PM3h 25mDailyKansas City to Des MoinesJefferson Lines
Full timetable
$40Book (carrier website)
8:05 PM11:30 PM3h 25mDailyKansas City to Des MoinesJefferson Lines
Full timetable
$40Book (carrier website)
8:35 PM New11:45 PM3h 10mDailyKansas City Bus Station to Des MoinesGreyhound
Full timetable
Fare not listed, no online booking link
11:25 PM3:20 AM +1 day3h 55mDailyKansas City to Des MoinesJefferson Lines
Full timetable
$40Book (carrier website)

Route map

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Where to board in Kansas City Where you get off in Des Moines The route of the busiest trip

Where to catch the bus in Kansas City

Where the bus stops in Des Moines

Return trip: Des Moines to Kansas City

Questions

How long is the bus from Kansas City to Des Moines?

The fastest direct bus takes 3 hours 10 minutes; the typical trip is 3 hours 25 minutes.

How much is the bus from Kansas City to Des Moines?

The standard one-way fare with Jefferson Lines is $40. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Greyhound aren't listed here; check its website.

What time is the first bus from Kansas City to Des Moines?

The earliest departure is at 8:35 AM (Daily) and the last at 11:25 PM (Daily).

Which bus companies go from Kansas City to Des Moines?

Jefferson Lines and Greyhound run direct buses on this route.

Where do I catch the bus in Kansas City?

Buses to Des Moines leave from Kansas City Bus Station.