MN → IA · about 228 miles
Minneapolis to Des Moines bus schedule
Jefferson Lines and Greyhound run 28 direct buses a week from Minneapolis to Des Moines. The fastest takes 5 hours; the first bus leaves at 12:50 PM and the last at 11:55 PM. The standard fare with Jefferson Lines is $55 one way.
Timetable data from · Schedule last changed
- Buses a week
- 28
- Fastest trip
- 5h 00m
- First bus
- 12:50 PM
- Last bus
- 11:55 PM
- Standard fare
- $55
A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Greyhound aren't listed here.
7 of the 28 buses a week stop at Minneapolis–Saint Paul International Airport (MSP).
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company | Standard fare & ticket |
|---|---|---|---|---|---|---|
| 12:50 PM | 6:35 PM | 5h 45m | Daily | Minneapolis to Des Moines | Jefferson Lines Full timetable | $55Book (carrier website) |
| 6:30 PM | 11:30 PM | 5h 00m | Daily | Minneapolis to Des Moines | Jefferson Lines Full timetable | $55Book (carrier website) |
| 9:45 PM | 3:15 AM +1 day | 5h 30m | Daily | Minneapolis to Des Moines | Jefferson Lines Full timetable | $55Book (carrier website) |
| 11:55 PM New | 5:05 AM +1 day | 5h 10m | Daily | Minneapolis Bus Station to Des Moines | Greyhound Full timetable | Fare not listed, no online booking link |
Route map
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Where to board in Minneapolis Where you get off in Des Moines The route of the busiest trip
Where to catch the bus in Minneapolis
Where the bus stops in Des Moines
- Des Moines bus stop Map of Des Moines bus stop (Google Maps)
Return trip: Des Moines to Minneapolis
Questions
How long is the bus from Minneapolis to Des Moines?
The fastest direct bus takes 5 hours; the typical trip is 5 hours 30 minutes.
How much is the bus from Minneapolis to Des Moines?
The standard one-way fare with Jefferson Lines is $55. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Greyhound aren't listed here; check its website.
What time is the first bus from Minneapolis to Des Moines?
The earliest departure is at 12:50 PM (Daily) and the last at 11:55 PM (Daily).
Which bus companies go from Minneapolis to Des Moines?
Jefferson Lines and Greyhound run direct buses on this route.
Where do I catch the bus in Minneapolis?
Buses to Des Moines leave from Minneapolis (Bus Station).
Does the bus from Minneapolis to Des Moines stop at Minneapolis–Saint Paul International Airport?
Yes, 7 of the 28 a week: at Minneapolis-St. Paul (Airport - MSP Terminal 1).