IA → IA · about 42 miles
Osceola to Des Moines bus schedule
Jefferson Lines runs 14 direct buses a week from Osceola to Des Moines. The fastest takes 45 minutes; the first bus leaves at 2:25 AM and the last at 10:45 PM. The standard fare is $10 one way.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 45m
- First bus
- 2:25 AM
- Last bus
- 10:45 PM
- Standard fare
- $10
A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.
Timetable
Every bus leaves from Osceola and arrives at Des Moines. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company | Ticket |
|---|---|---|---|---|---|
| 2:25 AM | 3:20 AM | 55m | Daily | Jefferson Lines Full timetable | Book (carrier website) |
| 10:45 PM | 11:30 PM | 45m | Daily | Jefferson Lines Full timetable | Book (carrier website) |
Route map
The map needs JavaScript.
Where to board in Osceola Where you get off in Des Moines The route of the busiest trip
Where to catch the bus in Osceola
Where the bus stops in Des Moines
- Des Moines bus stop Map of Des Moines bus stop (Google Maps)
Return trip: Des Moines to Osceola
Questions
How long is the bus from Osceola to Des Moines?
The fastest direct bus takes 45 minutes.
How much is the bus from Osceola to Des Moines?
The standard one-way fare with Jefferson Lines is $10. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.
What time is the first bus from Osceola to Des Moines?
The earliest departure is at 2:25 AM (Daily) and the last at 10:45 PM (Daily).
Which bus companies go from Osceola to Des Moines?
Jefferson Lines runs direct buses on this route.
Where do I catch the bus in Osceola?
Buses to Des Moines leave from Osceola Jefferson Lines bus stop.