OK → MO · about 457 miles
Oklahoma City to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Oklahoma City to St. Louis. The fastest takes 9 hours 20 minutes; the first bus leaves at 12:10 PM and the last at 9:45 PM.
Timetable data from · Schedule last changed
- Buses a week
- 7
- Fastest trip
- 9h 20m
- First bus
- 12:10 PM
- Last bus
- 9:45 PM
Timetable
Every bus leaves from Oklahoma City Bus Station and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 12:10 PM | 10:45 PM | 10h 35m | Daily | Greyhound Full timetable |
| 9:45 PM New | 7:05 AM +1 day | 9h 20m | Daily from Nov 3 | Greyhound Full timetable |
Route map
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Where to board in Oklahoma City Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Oklahoma City
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Oklahoma City
Questions
How long is the bus from Oklahoma City to St. Louis?
The fastest direct bus takes 9 hours 20 minutes.
What time is the first bus from Oklahoma City to St. Louis?
The earliest departure is at 12:10 PM (Daily) and the last at 9:45 PM (Daily).
Which bus companies go from Oklahoma City to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Oklahoma City?
Buses to St. Louis leave from Oklahoma City Bus Station.