MO → OK · about 457 miles
St. Louis to Oklahoma City bus schedule
Greyhound runs 14 direct buses a week from St. Louis to Oklahoma City. The fastest takes 9 hours 40 minutes; the first bus leaves at 1:20 AM and the last at 8:40 AM.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 9h 40m
- First bus
- 1:20 AM
- Last bus
- 8:40 AM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Oklahoma City Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:20 AM | 11:00 AM | 9h 40m | Daily | Greyhound Full timetable |
| 8:40 AM New | 6:25 PM | 9h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Oklahoma City The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Oklahoma City
Return trip: Oklahoma City to St. Louis
Questions
How long is the bus from St. Louis to Oklahoma City?
The fastest direct bus takes 9 hours 40 minutes.
What time is the first bus from St. Louis to Oklahoma City?
The earliest departure is at 1:20 AM (Daily) and the last at 8:40 AM (Daily).
Which bus companies go from St. Louis to Oklahoma City?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Oklahoma City leave from St Louis Bus Station.