NY → MO · about 875 miles
New York to St. Louis bus schedule
Greyhound runs 14 direct buses a week from New York to St. Louis. The fastest takes 23 hours; the first bus leaves at 9:55 AM and the last at 3:10 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 23h 00m
- First bus
- 9:55 AM
- Last bus
- 3:10 PM
Timetable
Every bus leaves from New York Manhattan 42 St Bus Terminal and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 9:55 AM | 7:55 AM +1 day | 23h 00m | Daily | Greyhound Full timetable |
| 3:10 PM | 3:10 PM +1 day | 25h 00m | Daily | Greyhound Full timetable |
Route map
The map needs JavaScript.
Where to board in New York Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in New York
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to New York
Questions
How long is the bus from New York to St. Louis?
The fastest direct bus takes 23 hours.
What time is the first bus from New York to St. Louis?
The earliest departure is at 9:55 AM (Daily) and the last at 3:10 PM (Daily).
Which bus companies go from New York to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in New York?
Buses to St. Louis leave from Port Authority Bus Terminal.