LA → MO · about 600 miles
New Orleans to St. Louis bus schedule
Greyhound runs 7 direct buses a week from New Orleans to St. Louis. The fastest takes 14 hours 40 minutes; every bus leaves at 8:20 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 14h 40m
- Leaves at
- 8:20 AM
Timetable
Every bus leaves from New Orleans Bus Station and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 8:20 AM | 11:00 PM | 14h 40m | Daily | Greyhound Full timetable |
Route map
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Where to board in New Orleans Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in New Orleans
- New Orleans Union Passenger Terminal Map of New Orleans Union Passenger Terminal (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to New Orleans
Questions
How long is the bus from New Orleans to St. Louis?
The fastest direct bus takes 14 hours 40 minutes.
What time is the first bus from New Orleans to St. Louis?
Every departure is at 8:20 AM (Daily).
Which bus companies go from New Orleans to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in New Orleans?
Buses to St. Louis leave from New Orleans Union Passenger Terminal.