KS → MO · about 344 miles
Manhattan to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Manhattan to St. Louis. The fastest takes 8 hours 5 minutes; every bus leaves at 12:05 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 8h 05m
- Leaves at
- 12:05 AM
Timetable
Every bus leaves from Manhattan KS and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 12:05 AM | 8:10 AM | 8h 05m | Daily | Greyhound Full timetable |
Route map
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Where to board in Manhattan Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Manhattan
- Manhattan Greyhound bus stop Map of Manhattan Greyhound bus stop (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Manhattan
Questions
How long is the bus from Manhattan to St. Louis?
The fastest direct bus takes 8 hours 5 minutes.
What time is the first bus from Manhattan to St. Louis?
Every departure is at 12:05 AM (Daily).
Which bus companies go from Manhattan to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Manhattan?
Buses to St. Louis leave from Manhattan Greyhound bus stop.