MO → KS · about 344 miles
St. Louis to Manhattan bus schedule
Greyhound runs 7 direct buses a week from St. Louis to Manhattan. The fastest takes 8 hours 15 minutes; every bus leaves at 11:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 8h 15m
- Leaves at
- 11:45 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Manhattan KS. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 11:45 PM | 8:00 AM +1 day | 8h 15m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Manhattan The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Manhattan
- Manhattan Greyhound bus stop Map of Manhattan Greyhound bus stop (Google Maps)
Return trip: Manhattan to St. Louis
Questions
How long is the bus from St. Louis to Manhattan?
The fastest direct bus takes 8 hours 15 minutes.
What time is the first bus from St. Louis to Manhattan?
Every departure is at 11:45 PM (Daily).
Which bus companies go from St. Louis to Manhattan?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Manhattan leave from St Louis Bus Station.