KY → MO · about 177 miles
Madisonville to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Madisonville to St. Louis. The fastest takes 4 hours 45 minutes; every bus leaves at 11:10 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 4h 45m
- Leaves at
- 11:10 AM
Timetable
Every bus leaves from Madisonville KY (MDV) and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 11:10 AM | 3:55 PM | 4h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in Madisonville Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Madisonville
- Madisonville KY (MDV) Map of Madisonville KY (MDV) (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Madisonville
Questions
How long is the bus from Madisonville to St. Louis?
The fastest direct bus takes 4 hours 45 minutes.
What time is the first bus from Madisonville to St. Louis?
Every departure is at 11:10 AM (Daily).
Which bus companies go from Madisonville to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Madisonville?
Buses to St. Louis leave from Madisonville KY (MDV).