MS → MO · about 437 miles
Jackson to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Jackson to St. Louis. The fastest takes 10 hours 5 minutes; every bus leaves at 12:55 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 10h 05m
- Leaves at
- 12:55 PM
Timetable
Every bus leaves from Jackson Union Station and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 12:55 PM | 11:00 PM | 10h 05m | Daily | Greyhound Full timetable |
Route map
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Where to board in Jackson Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Jackson
- Jackson Union Station Map of Jackson Union Station (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Jackson
Questions
How long is the bus from Jackson to St. Louis?
The fastest direct bus takes 10 hours 5 minutes.
What time is the first bus from Jackson to St. Louis?
Every departure is at 12:55 PM (Daily).
Which bus companies go from Jackson to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Jackson?
Buses to St. Louis leave from Jackson Union Station.