MO → MS · about 437 miles
St. Louis to Jackson bus schedule
Greyhound runs 7 direct buses a week from St. Louis to Jackson. The fastest takes 11 hours 45 minutes; every bus leaves at 1:00 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 11h 45m
- Leaves at
- 1:00 AM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Jackson Union Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:00 AM | 12:45 PM | 11h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Jackson The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Jackson
- Jackson Union Station Map of Jackson Union Station (Google Maps)
Return trip: Jackson to St. Louis
Questions
How long is the bus from St. Louis to Jackson?
The fastest direct bus takes 11 hours 45 minutes.
What time is the first bus from St. Louis to Jackson?
Every departure is at 1:00 AM (Daily).
Which bus companies go from St. Louis to Jackson?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Jackson leave from St Louis Bus Station.