OH → KY · about 190 miles
Columbus to Louisville bus schedule
Barons Bus Lines and Greyhound run 14 direct buses a week from Columbus to Louisville. The fastest takes 4 hours 55 minutes; the first bus leaves at 5:20 AM and the last at 4:05 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 4h 55m
- First bus
- 5:20 AM
- Last bus
- 4:05 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company | Ticket |
|---|---|---|---|---|---|---|
| 5:20 AM | 12:10 PM | 6h 50m | Daily | Columbus E Mound St to Louisville Bus Station | Greyhound Full timetable | No online booking link |
| 4:05 PM | 9:00 PM | 4h 55m | Daily | Columbus (E Mound St) to Louisville | Barons Bus Lines Full timetable | Book (carrier website) |
Route map
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Where to board in Columbus Where you get off in Louisville The route of the busiest trip
Where to catch the bus in Columbus
Where the bus stops in Louisville
- Louisville Bus Station Map of Louisville Bus Station (Google Maps)
Return trip: Louisville to Columbus
Questions
How long is the bus from Columbus to Louisville?
The fastest direct bus takes 4 hours 55 minutes.
What time is the first bus from Columbus to Louisville?
The earliest departure is at 5:20 AM (Daily) and the last at 4:05 PM (Daily).
Which bus companies go from Columbus to Louisville?
Barons Bus Lines and Greyhound run direct buses on this route.
Where do I catch the bus in Columbus?
Buses to Louisville leave from Columbus (E Mound St).