OH → KY · about 309 miles
Cleveland to Louisville bus schedule
Barons Bus Lines and Greyhound run 14 direct buses a week from Cleveland to Louisville. The fastest takes 8 hours; the first bus leaves at 2:45 AM and the last at 1:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 8h 00m
- First bus
- 2:45 AM
- Last bus
- 1:00 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company | Ticket |
|---|---|---|---|---|---|---|
| 2:45 AM | 12:10 PM | 9h 25m | Daily | Cleveland Bus Station (Brook Park) to Louisville Bus Station | Greyhound Full timetable | No online booking link |
| 1:00 PM | 9:00 PM | 8h 00m | Daily | Cleveland (Brook Park) to Louisville | Barons Bus Lines Full timetable | Book (carrier website) |
Route map
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Where to board in Cleveland Where you get off in Louisville The route of the busiest trip
Where to catch the bus in Cleveland
Where the bus stops in Louisville
- Louisville Bus Station Map of Louisville Bus Station (Google Maps)
Return trip: Louisville to Cleveland
Questions
How long is the bus from Cleveland to Louisville?
The fastest direct bus takes 8 hours.
What time is the first bus from Cleveland to Louisville?
The earliest departure is at 2:45 AM (Daily) and the last at 1:00 PM (Daily).
Which bus companies go from Cleveland to Louisville?
Barons Bus Lines and Greyhound run direct buses on this route.
Where do I catch the bus in Cleveland?
Buses to Louisville leave from Cleveland (Brook Park).