OH → NY · about 180 miles
Cleveland to Buffalo bus & train schedule
Barons Bus Lines, Amtrak, FlixBus and Greyhound run 37 direct buses and trains a week from Cleveland to Buffalo. The fastest takes 3 hours 3 minutes; the first departure leaves at 4:30 AM and the last at 7:30 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 37
- Fastest trip
- 3h 03m
- First departure
- 4:30 AM
- Last departure
- 7:30 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company | Ticket |
|---|---|---|---|---|---|---|
| 4:30 AM | 8:00 AM | 3h 30m | Daily | Cleveland Bus Station (Brook Park) to Buffalo | Greyhound Full timetable | No online booking link |
| 5:50 AM | 8:53 AM | 3h 03m | Daily | Cleveland to Buffalo Depew Station | Amtrak Full timetable | No online booking link |
| 12:45 PM | 4:45 PM | 4h 00m | Daily | Cleveland Bus Station (Brook Park) to Buffalo | Greyhound Full timetable | No online booking link |
| 5:45 PM New | 9:35 PM | 3h 50m | Mon, Wed, Fri, Sat, Sun | Cleveland th St & Rockwell Av to Buffalo | FlixBus Full timetable | No online booking link |
| 7:30 PM | 10:55 PM | 3h 25m | Daily | Cleveland (Brook Park) to Buffalo | Barons Bus Lines Full timetable | Book (carrier website) |
Route map
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Where to board in Cleveland Where you get off in Buffalo The route of the busiest trip
Where to board in Cleveland
Where buses and trains stop in Buffalo
Return trip: Buffalo to Cleveland
Questions
How long is the bus or train from Cleveland to Buffalo?
The fastest direct bus or train takes 3 hours 3 minutes; the typical trip is 3 hours 3 minutes.
What time is the first departure from Cleveland to Buffalo?
The earliest departure is at 4:30 AM (Daily) and the last at 7:30 PM (Daily).
Which bus and rail companies go from Cleveland to Buffalo?
Barons Bus Lines, Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Cleveland?
Buses and trains to Buffalo leave from Cleveland (Brook Park), Cleveland Amtrak station and Cleveland th St & Rockwell Av.