Station in Buffalo, NY
Buffalo Depew Station
Amtrak stops here: 69 departures a week to 30 cities and towns. The first train leaves at 12:39 AM and the last at 9:27 PM.
Timetable data from
- Departures a week
- 69
- Destinations
- 30
- Rail companies
- 1
- Arrivals a week
- 69
Where the station is
Nearest address 55 Dick Road, Town of Cheektowaga, NY 14043 (© OpenStreetMap contributors)
In Buffalo, NY, at 42.90702, -78.72658. Open in Google Maps of Buffalo Depew Station (Google Maps) · Directions to Buffalo Depew Station (Google Maps)
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Where you can go from here
Direct trains from this station. Pick a destination for its full timetable.
| Destination | Trains a week | Fastest | Rail company |
|---|---|---|---|
| Rochester, NY | 34 trains a week | Fastest 50m | Amtrak |
| Syracuse, NY | 34 trains a week | Fastest 2h 04m | Amtrak |
| Utica, NY | 34 trains a week | Fastest 3h 08m | Amtrak |
| Schenectady, NY | 34 trains a week | Fastest 4h 36m | Amtrak |
| Albany, NY | 34 trains a week | Fastest 4h 57m | Amtrak |
| Rhinecliff, NY | 27 trains a week | Fastest 6h 04m | Amtrak |
| Poughkeepsie, NY | 27 trains a week | Fastest 6h 25m | Amtrak |
| Croton-on-Hudson, NY | 27 trains a week | Fastest 7h 05m | Amtrak |
| New York, NY | 27 trains a week | Fastest 8h 00m | Amtrak |
| Niagara Falls, NY | 21 trains a week | Fastest 1h 01m | Amtrak |
| Rome, NY | 20 trains a week | Fastest 2h 52m | Amtrak |
| Amsterdam, NY | 20 trains a week | Fastest 4h 10m | Amtrak |
| Hudson, NY | 20 trains a week | Fastest 5h 41m | Amtrak |
| Erie, PA | 14 trains a week | Fastest 1h 31m | Amtrak |
| Cleveland, OH | 14 trains a week | Fastest 3h 14m | Amtrak |
| Elyria, OH | 14 trains a week | Fastest 3h 53m | Amtrak |
| Sandusky, OH | 14 trains a week | Fastest 4h 30m | Amtrak |
| Toledo, OH | 14 trains a week | Fastest 5h 34m | Amtrak |
| Bryan, OH | 14 trains a week | Fastest 6h 44m | Amtrak |
| Waterloo, IN | 14 trains a week | Fastest 7h 12m | Amtrak |
| Elkhart, IN | 14 trains a week | Fastest 8h 04m | Amtrak |
| South Bend, IN | 14 trains a week | Fastest 8h 25m | Amtrak |
| Chicago, IL | 14 trains a week | Fastest 10h 33m | Amtrak |
| Yonkers, NY | 13 trains a week | Fastest 7h 32m | Amtrak |
| Toronto, ON | 7 trains a week | Fastest 4h 18m | Amtrak |
| Pittsfield, MA | 7 trains a week | Fastest 7h 25m | Amtrak |
| Springfield, MA | 7 trains a week | Fastest 8h 44m | Amtrak |
| Worcester, MA | 7 trains a week | Fastest 10h 25m | Amtrak |
| Framingham, MA | 7 trains a week | Fastest 10h 53m | Amtrak |
| Boston, MA | 7 trains a week | Fastest 11h 19m | Amtrak |
Departures
Every train leaving this station, by time of day. Times are local. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Going to | Days | Rail company |
|---|---|---|---|
| 12:39 AM | Chicago | Daily | Amtrak |
| 12:39 AM | Chicago | Daily | Amtrak |
| 4:35 AM | New York | Daily | Amtrak |
| 4:45 AM | New York | Daily from Nov 2 | Amtrak |
| 7:29 AM | New York | Daily | Amtrak |
| 7:39 AM | New York | Daily from Nov 2 | Amtrak |
| 9:05 AM | Boston | Daily | Amtrak |
| 9:05 AM | New York | Daily | Amtrak |
| 12:30 PM | New York | Tue–Sun | Amtrak |
| 12:40 PM | New York | Daily from Nov 2 | Amtrak |
| 3:19 PM | Toronto | Daily from Nov 2 | Amtrak |
| 3:25 PM | Toronto | Daily | Amtrak |
| 6:34 PM | Niagara Falls | Daily from Nov 2 | Amtrak |
| 6:40 PM | Niagara Falls | Daily | Amtrak |
| 9:21 PM | Niagara Falls | Daily from Nov 2 | Amtrak |
| 9:27 PM | Niagara Falls | Daily | Amtrak |
Trains arriving from
Questions
Which rail companies stop at Buffalo Depew Station?
Amtrak stops at Buffalo Depew Station in Buffalo, NY.
What time does the first train leave Buffalo Depew Station?
The first departure is at 12:39 AM (Daily) and the last at 9:27 PM (Daily). Times are local.
Where can I go from Buffalo Depew Station?
Direct trains go to 30 cities and towns, including Rochester, Syracuse, Utica, Schenectady and Albany.
Where is Buffalo Depew Station?
Buffalo Depew Station is in Buffalo, NY, at 55 Dick Road, Town of Cheektowaga, NY 14043 (the nearest address on OpenStreetMap), at latitude 42.90702, longitude -78.72658.