NY → MA · about 396 miles
Buffalo to Boston bus & train schedule
Amtrak and Greyhound run 14 direct buses and trains a week from Buffalo to Boston. The fastest takes 10 hours 5 minutes; the first departure leaves at 8:20 AM and the last at 9:05 AM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 14
- Fastest trip
- 10h 05m
- First departure
- 8:20 AM
- Last departure
- 9:05 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 8:20 AM | 6:25 PM | 10h 05m | Daily | Buffalo to Boston South Station | Greyhound Full timetable |
| 9:05 AM | 8:24 PM | 11h 19m | Daily | Buffalo Depew Station to Boston | Amtrak Full timetable |
Route map
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Where to board in Buffalo Where you get off in Boston The route of the busiest trip
Where to board in Buffalo
Where buses and trains stop in Boston
Return trip: Boston to Buffalo
Questions
How long is the bus or train from Buffalo to Boston?
The fastest direct bus or train takes 10 hours 5 minutes; the typical trip is 11 hours 19 minutes.
What time is the first departure from Buffalo to Boston?
The earliest departure is at 8:20 AM (Daily) and the last at 9:05 AM (Daily).
Which bus and rail companies go from Buffalo to Boston?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in Buffalo?
Buses and trains to Boston leave from Buffalo Depew Station and Buffalo bus stop.