NY → NY · about 135 miles
Buffalo to Syracuse bus & train schedule
Adirondack Trailways, Amtrak, FlixBus, Greyhound and OurBus run 113 direct buses and trains a week from Buffalo to Syracuse. The fastest takes 2 hours 19 minutes; the first departure leaves at 12:55 AM and the last at 11:15 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 113
- Fastest trip
- 2h 19m
- First departure
- 12:55 AM
- Last departure
- 11:15 PM
32 of the 113 buses and trains a week stop at Buffalo Niagara International Airport (BUF).
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company | Ticket |
|---|---|---|---|---|---|---|
| 12:55 AM | 3:20 AM | 2h 25m | Daily | Buffalo to Syracuse Bus Station | Greyhound Full timetable | No online booking link |
| 4:18 AM | 6:53 AM | 2h 35m | Daily | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 4:28 AM | 6:57 AM | 2h 29m | Daily from Nov 2 | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 5:00 AM New | 8:00 AM | 3h 00m | Mon from Nov 30 | Buffalo, NY (SUNY Buffalo North Campus area - Maple Road Sunoco station at 4641 Maple Road) to Syracuse, NY (Syracuse University- Waverly Ave. between Walnut Place and University Ave.) | OurBus Full timetable | No online booking link |
| 5:30 AM | 8:25 AM | 2h 55m | Mon, Tue, Fri, Sat, Sun | Buffalo to Syracuse Bus Station | FlixBus Full timetable | No online booking link |
| 6:00 AM | 9:15 AM | 3h 15m | Mon, Thu, Fri, Sat, Sun | Buffalo to Syracuse | Adirondack Trailways Full timetable | Book (carrier website) |
| 7:12 AM | 9:45 AM | 2h 33m | Daily | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 7:22 AM | 9:49 AM | 2h 27m | Daily from Nov 2 | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 8:20 AM | 11:20 AM | 3h 00m | Daily | Buffalo to Syracuse Bus Station | Greyhound Full timetable | No online booking link |
| 9:00 AM | 12:05 PM | 3h 05m | Daily | Buffalo to Syracuse Bus Station | FlixBus Full timetable | No online booking link |
| 9:05 AM | 11:28 AM | 2h 23m | Daily | Buffalo Depew Station to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 11:35 AM | 2:55 PM | 3h 20m | Daily | Buffalo to Syracuse | Adirondack Trailways Full timetable | Book (carrier website) |
| 12:15 PM | 2:40 PM | 2h 25m | Tue–Sun | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 12:25 PM | 2:44 PM | 2h 19m | Daily from Nov 2 | Buffalo to Syracuse Regional Transportation Center | Amtrak Full timetable | No online booking link |
| 2:25 PM | 5:40 PM | 3h 15m | Daily from Nov 19 | Buffalo, NY (SUNY Buffalo North Campus area - Maple Road Sunoco station at 4641 Maple Road) to Syracuse, NY (Syracuse University- Waverly Ave. between Walnut Place and University Ave.) | OurBus Full timetable | No online booking link |
| 3:40 PM | 6:45 PM | 3h 05m | Daily | Buffalo to Syracuse Bus Station | Greyhound Full timetable | No online booking link |
| 5:20 PM | 8:25 PM | 3h 05m | Daily | Buffalo to Syracuse Bus Station | Greyhound Full timetable | No online booking link |
| 8:45 PM | 11:45 PM | 3h 00m | Daily | Buffalo to Syracuse Bus Station | Greyhound Full timetable | No online booking link |
| 10:00 PM | 1:05 AM +1 day | 3h 05m | Daily | Buffalo to Syracuse Bus Station | FlixBus Full timetable | No online booking link |
| 11:00 PM | 2:25 AM +1 day | 3h 25m | Daily except Tue | Buffalo to Syracuse Bus Station | FlixBus Full timetable | No online booking link |
| 11:15 PM | 2:25 AM +1 day | 3h 10m | Daily | Buffalo to Syracuse | Adirondack Trailways Full timetable | Book (carrier website) |
Route map
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Where to board in Buffalo Where you get off in Syracuse The route of the busiest trip
Where to board in Buffalo
Where buses and trains stop in Syracuse
Return trip: Syracuse to Buffalo
Questions
How long is the bus or train from Buffalo to Syracuse?
The fastest direct bus or train takes 2 hours 19 minutes; the typical trip is 2 hours 55 minutes.
What time is the first departure from Buffalo to Syracuse?
The earliest departure is at 12:55 AM (Daily) and the last at 11:15 PM (Daily).
Which bus and rail companies go from Buffalo to Syracuse?
Adirondack Trailways, Amtrak, FlixBus, Greyhound and OurBus run direct buses and trains on this route.
Where do I board in Buffalo?
Buses and trains to Syracuse leave from Buffalo bus stop, Buffalo Depew Station and Buffalo (SUNY Buffalo North Campus area).
Does the bus or train from Buffalo to Syracuse stop at Buffalo Niagara International Airport?
Yes, 32 of the 113 a week: at Buffalo (Airport).