NY → IL · about 457 miles
Buffalo to Chicago train schedule
Amtrak runs 14 direct trains a week from Buffalo to Chicago. The fastest takes 10 hours 33 minutes; every train leaves at 12:39 AM.
Timetable data from · No schedule changes since at least
- Trains a week
- 14
- Fastest trip
- 10h 33m
- Leaves at
- 12:39 AM
Timetable
Every train leaves from Buffalo Depew Station and arrives at Chicago Union Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 12:39 AM | 10:12 AM | 10h 33m | Daily | Amtrak Full timetable |
| 12:39 AM | 11:12 AM | 11h 33m | Mon | Amtrak Full timetable |
Route map
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Where to board in Buffalo Where you get off in Chicago The route of the busiest trip
Where to catch the train in Buffalo
Where the train stops in Chicago
Return trip: Chicago to Buffalo
Questions
How long is the train from Buffalo to Chicago?
The fastest direct train takes 10 hours 33 minutes; the typical trip is 10 hours 33 minutes.
What time is the first train from Buffalo to Chicago?
Every departure is at 12:39 AM (Daily).
Which rail companies go from Buffalo to Chicago?
Amtrak runs direct trains on this route.
Where do I catch the train in Buffalo?
Trains to Chicago leave from Buffalo Depew Station.