IN → IL · about 108 miles
Lafayette to Chicago bus & train schedule
Amtrak, FlixBus and Greyhound run 65 direct buses and trains a week from Lafayette to Chicago. The fastest takes 2 hours 5 minutes; the first departure leaves at 4:30 AM and the last at 7:05 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 65
- Fastest trip
- 2h 05m
- First departure
- 4:30 AM
- Last departure
- 7:05 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 4:30 AM | 5:40 AM | 2h 10m | Daily except Wed | Lafayette North 3rd Street to Chicago 95th / Dan Ryan | FlixBus Full timetable |
| 6:40 AM | 8:00 AM | 2h 20m | Daily | Lafayette North 3rd Street to Chicago Train Station | Greyhound Full timetable |
| 8:01 AM | 10:25 AM | 3h 24m | Mon, Thu, Sat | Lafayette Amtrak Station to Chicago Union Station | Amtrak Full timetable |
| 8:25 AM | 10:40 AM | 3h 15m | Daily | Lafayette North 3rd Street to Chicago Bus Station | Greyhound Full timetable |
| 10:45 AM | 12:00 PM | 2h 15m | Daily except Tue | Lafayette North 3rd Street to Chicago Bus Station | FlixBus Full timetable |
| 11:50 AM | 1:15 PM | 2h 25m | Daily | Lafayette North 3rd Street to Chicago 95th / Dan Ryan | Greyhound Full timetable |
| 1:55 PM | 3:15 PM | 2h 20m | Daily | Lafayette North 3rd Street to Chicago Bus Station | Greyhound Full timetable |
| 2:45 PM | 4:15 PM | 2h 30m | Daily except Tue | Lafayette North 3rd Street to Chicago Bus Station | FlixBus Full timetable |
| 5:20 PM | 6:55 PM | 2h 35m | Thu, Fri | Lafayette North 3rd Street to Chicago Bus Station | FlixBus Full timetable |
| 6:05 PM | 7:20 PM | 2h 15m | Daily | Lafayette North 3rd Street to Chicago Bus Station | FlixBus Full timetable |
| 7:05 PM | 8:10 PM | 2h 05m | Daily | Lafayette North 3rd Street to Chicago Bus Station | Greyhound Full timetable |
Route map
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Where to board in Lafayette Where you get off in Chicago The route of the busiest trip
Where to board in Lafayette
Where buses and trains stop in Chicago
- Chicago Union Station Map of Chicago Union Station (Google Maps)
- Chicago Bus Station Map of Chicago Bus Station (Google Maps)
- Chicago 95th / Dan Ryan Map of Chicago 95th / Dan Ryan (Google Maps)
- W Jackson Blvd, after S Clinton St (across from Union Station) Map of W Jackson Blvd, after S Clinton St (across from Union Station) (Google Maps)
Return trip: Chicago to Lafayette
Questions
How long is the bus or train from Lafayette to Chicago?
The fastest direct bus or train takes 2 hours 5 minutes; the typical trip is 2 hours 25 minutes.
What time is the first departure from Lafayette to Chicago?
The earliest departure is at 4:30 AM (Daily except Wed) and the last at 7:05 PM (Daily).
Which bus and rail companies go from Lafayette to Chicago?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Lafayette?
Buses and trains to Chicago leave from Lafayette Amtrak Station and Lafayette North 3rd Street.