IL → IN · about 108 miles
Chicago to Lafayette bus & train schedule
Amtrak, FlixBus and Greyhound run 54 direct buses and trains a week from Chicago to Lafayette. The fastest takes 2 hours 10 minutes; the first departure leaves at 6:10 AM and the last at 7:15 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 54
- Fastest trip
- 2h 10m
- First departure
- 6:10 AM
- Last departure
- 7:15 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:10 AM | 9:20 AM | 2h 10m | Daily | Chicago Bus Station to Lafayette North 3rd Street | Greyhound Full timetable |
| 7:00 AM | 10:45 AM | 2h 45m | Mon, Tue, Fri, Sat, Sun | Chicago Bus Station to Lafayette North 3rd Street | FlixBus Full timetable |
| 8:00 AM | 11:15 AM | 2h 15m | Daily | Chicago Bus Station to Lafayette North 3rd Street | FlixBus Full timetable |
| 9:55 AM | 1:35 PM | 2h 40m | Daily | Chicago Bus Station to Lafayette North 3rd Street | Greyhound Full timetable |
| 10:30 AM | 1:45 PM | 2h 15m | Daily except Wed | Chicago Bus Station to Lafayette North 3rd Street | FlixBus Full timetable |
| 11:30 AM | 2:50 PM | 2h 20m | Daily except Wed | Chicago Bus Station to Lafayette North 3rd Street | FlixBus Full timetable |
| 12:40 PM | 4:55 PM | 3h 15m | Daily | Chicago Bus Station to Lafayette North 3rd Street | Greyhound Full timetable |
| 5:55 PM | 9:56 PM | 3h 01m | Tue, Thu, Sat | Chicago Union Station to Lafayette Amtrak Station | Amtrak Full timetable |
| 7:15 PM | 10:55 PM | 2h 40m | Daily except Tue | Chicago Bus Station to Lafayette North 3rd Street | FlixBus Full timetable |
Route map
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Where to board in Chicago Where you get off in Lafayette The route of the busiest trip
Where to board in Chicago
Where buses and trains stop in Lafayette
Return trip: Lafayette to Chicago
Questions
How long is the bus or train from Chicago to Lafayette?
The fastest direct bus or train takes 2 hours 10 minutes; the typical trip is 2 hours 45 minutes.
What time is the first departure from Chicago to Lafayette?
The earliest departure is at 6:10 AM (Daily) and the last at 7:15 PM (Daily except Tue).
Which bus and rail companies go from Chicago to Lafayette?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Chicago?
Buses and trains to Lafayette leave from Chicago Union Station and Chicago Bus Station.