IL → IN · about 165 miles
Chicago to Indianapolis bus & train schedule
Amtrak, FlixBus and Greyhound run 68 direct buses and trains a week from Chicago to Indianapolis. The fastest takes 3 hours 5 minutes; the first departure leaves at 6:10 AM and the last at 10:50 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 68
- Fastest trip
- 3h 05m
- First departure
- 6:10 AM
- Last departure
- 10:50 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:10 AM | 10:45 AM | 3h 35m | Daily | Chicago Bus Station to Indianapolis Bus Station | Greyhound Full timetable |
| 7:00 AM | 11:50 AM | 3h 50m | Mon, Tue, Fri, Sat, Sun | Chicago Bus Station to Indianapolis W Vermont St | FlixBus Full timetable |
| 8:00 AM | 12:45 PM | 3h 45m | Daily | Chicago Bus Station to Indianapolis W Vermont St | FlixBus Full timetable |
| 9:55 AM | 3:05 PM | 4h 10m | Daily | Chicago Bus Station to Indianapolis Bus Station | Greyhound Full timetable |
| 10:30 AM | 3:00 PM | 3h 30m | Daily except Wed | Chicago Bus Station to Indianapolis W Vermont St | FlixBus Full timetable |
| 11:30 AM | 4:10 PM | 3h 40m | Daily except Wed | Chicago Bus Station to Indianapolis W Vermont St | FlixBus Full timetable |
| 12:40 PM | 6:30 PM | 4h 50m | Daily | Chicago Bus Station to Indianapolis Bus Station | Greyhound Full timetable |
| 2:45 PM | 6:50 PM | 3h 05m | Daily | Chicago Bus Station to Indianapolis Bus Station | Greyhound Full timetable |
| 5:55 PM | 11:49 PM | 4h 54m | Tue, Thu, Sat | Chicago Union Station to Indianapolis | Amtrak Full timetable |
| 7:15 PM | 12:05 AM +1 day | 3h 50m | Daily except Tue | Chicago Bus Station to Indianapolis W Vermont St | FlixBus Full timetable |
| 10:50 PM | 4:15 AM +1 day | 4h 25m | Daily | Chicago Bus Station to Indianapolis Bus Station | Greyhound Full timetable |
Route map
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Where to board in Chicago Where you get off in Indianapolis The route of the busiest trip
Where to board in Chicago
Where buses and trains stop in Indianapolis
Return trip: Indianapolis to Chicago
Questions
How long is the bus or train from Chicago to Indianapolis?
The fastest direct bus or train takes 3 hours 5 minutes; the typical trip is 3 hours 50 minutes.
What time is the first departure from Chicago to Indianapolis?
The earliest departure is at 6:10 AM (Daily) and the last at 10:50 PM (Daily).
Which bus and rail companies go from Chicago to Indianapolis?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Chicago?
Buses and trains to Indianapolis leave from Chicago Union Station and Chicago Bus Station.