OH → IN · about 169 miles
Columbus to Indianapolis bus schedule
FlixBus and Greyhound run 26 direct buses a week from Columbus to Indianapolis. The fastest takes 3 hours 30 minutes; the first bus leaves at 4:40 AM and the last at 11:50 PM.
Timetable data from · Schedule last changed
- Buses a week
- 26
- Fastest trip
- 3h 30m
- First bus
- 4:40 AM
- Last bus
- 11:50 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 4:40 AM | 9:20 AM | 4h 40m | Daily | Columbus E Mound St to Indianapolis Bus Station | Greyhound Full timetable |
| 9:45 AM | 1:15 PM | 3h 30m | Daily except Tue | Columbus Downtown to Indianapolis W Vermont St | FlixBus Full timetable |
| 11:30 PM | 3:00 AM +1 day | 3h 30m | Daily except Tue | Columbus Downtown to Indianapolis W Vermont St | FlixBus Full timetable |
| 11:50 PM | 4:10 AM +1 day | 4h 20m | Daily | Columbus E Mound St to Indianapolis Bus Station | Greyhound Full timetable |
Route map
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Where to board in Columbus Where you get off in Indianapolis The route of the busiest trip
Where to catch the bus in Columbus
Where the bus stops in Indianapolis
Return trip: Indianapolis to Columbus
Questions
How long is the bus from Columbus to Indianapolis?
The fastest direct bus takes 3 hours 30 minutes; the typical trip is 4 hours 20 minutes.
What time is the first bus from Columbus to Indianapolis?
The earliest departure is at 4:40 AM (Daily) and the last at 11:50 PM (Daily).
Which bus companies go from Columbus to Indianapolis?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Columbus?
Buses to Indianapolis leave from Columbus Downtown and Columbus (E Mound St).