IN → IL · about 165 miles
Indianapolis to Chicago bus & train schedule
Amtrak, FlixBus and Greyhound run 65 direct buses and trains a week from Indianapolis to Chicago. The fastest takes 3 hours 25 minutes; the first departure leaves at 3:15 AM and the last at 5:35 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 65
- Fastest trip
- 3h 25m
- First departure
- 3:15 AM
- Last departure
- 5:35 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 3:15 AM | 5:40 AM | 3h 25m | Daily except Wed | Indianapolis W Vermont St to Chicago 95th / Dan Ryan | FlixBus Full timetable |
| 5:20 AM | 8:00 AM | 3h 40m | Daily | Indianapolis Bus Station to Chicago Train Station | Greyhound Full timetable |
| 6:25 AM | 10:25 AM | 5h 00m | Mon, Thu, Sat | Indianapolis to Chicago Union Station | Amtrak Full timetable |
| 6:40 AM | 10:40 AM | 5h 00m | Daily | Indianapolis Bus Station to Chicago Bus Station | Greyhound Full timetable |
| 9:30 AM | 12:00 PM | 3h 30m | Daily except Tue | Indianapolis W Vermont St to Chicago Bus Station | FlixBus Full timetable |
| 10:25 AM | 1:15 PM | 3h 50m | Daily | Indianapolis Bus Station to Chicago 95th / Dan Ryan | Greyhound Full timetable |
| 12:35 PM | 3:15 PM | 3h 40m | Daily | Indianapolis Bus Station to Chicago Bus Station | Greyhound Full timetable |
| 1:30 PM | 4:15 PM | 3h 45m | Daily except Tue | Indianapolis W Vermont St to Chicago Bus Station | FlixBus Full timetable |
| 4:10 PM | 6:55 PM | 3h 45m | Thu, Fri | Indianapolis W Vermont St to Chicago Bus Station | FlixBus Full timetable |
| 4:40 PM | 7:20 PM | 3h 40m | Daily | Indianapolis W Vermont St to Chicago Bus Station | FlixBus Full timetable |
| 5:35 PM | 8:10 PM | 3h 35m | Daily | Indianapolis Bus Station to Chicago Bus Station | Greyhound Full timetable |
Route map
The map needs JavaScript.
Where to board in Indianapolis Where you get off in Chicago The route of the busiest trip
Where to board in Indianapolis
Where buses and trains stop in Chicago
- Chicago Union Station Map of Chicago Union Station (Google Maps)
- Chicago Bus Station Map of Chicago Bus Station (Google Maps)
- Chicago 95th / Dan Ryan Map of Chicago 95th / Dan Ryan (Google Maps)
- W Jackson Blvd, after S Clinton St (across from Union Station) Map of W Jackson Blvd, after S Clinton St (across from Union Station) (Google Maps)
Return trip: Chicago to Indianapolis
Questions
How long is the bus or train from Indianapolis to Chicago?
The fastest direct bus or train takes 3 hours 25 minutes; the typical trip is 3 hours 45 minutes.
What time is the first departure from Indianapolis to Chicago?
The earliest departure is at 3:15 AM (Daily except Wed) and the last at 5:35 PM (Daily).
Which bus and rail companies go from Indianapolis to Chicago?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Indianapolis?
Buses and trains to Chicago leave from Indianapolis Bus Station and Indianapolis W Vermont St.