KY → IN · about 162 miles
Louisville to Lafayette bus schedule
Greyhound runs 28 direct buses a week from Louisville to Lafayette. The fastest takes 3 hours 35 minutes; the first bus leaves at 3:00 AM and the last at 2:45 PM.
Timetable data from · Schedule last changed
- Buses a week
- 28
- Fastest trip
- 3h 35m
- First bus
- 3:00 AM
- Last bus
- 2:45 PM
Timetable
Every bus leaves from Louisville Bus Station and arrives at Lafayette North 3rd Street. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:00 AM | 6:35 AM | 3h 35m | Daily | Greyhound Full timetable |
| 7:35 AM | 11:45 AM | 4h 10m | Daily | Greyhound Full timetable |
| 10:15 AM | 1:50 PM | 3h 35m | Daily | Greyhound Full timetable |
| 2:45 PM | 7:00 PM | 4h 15m | Daily | Greyhound Full timetable |
Route map
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Where to board in Louisville Where you get off in Lafayette The route of the busiest trip
Where to catch the bus in Louisville
- Louisville Bus Station Map of Louisville Bus Station (Google Maps)
Where the bus stops in Lafayette
Return trip: Lafayette to Louisville
Questions
How long is the bus from Louisville to Lafayette?
The fastest direct bus takes 3 hours 35 minutes; the typical trip is 4 hours 10 minutes.
What time is the first bus from Louisville to Lafayette?
The earliest departure is at 3:00 AM (Daily) and the last at 2:45 PM (Daily).
Which bus companies go from Louisville to Lafayette?
Greyhound runs direct buses on this route.
Where do I catch the bus in Louisville?
Buses to Lafayette leave from Louisville Bus Station.