KY → TN · about 191 miles
Louisville to Manchester bus schedule
Greyhound runs 28 direct buses a week from Louisville to Manchester. The fastest takes 4 hours 50 minutes; the first bus leaves at 3:35 AM and the last at 6:30 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 28
- Fastest trip
- 4h 50m
- First bus
- 3:35 AM
- Last bus
- 6:30 PM
Timetable
Every bus leaves from Louisville Bus Station and arrives at Manchester Shell. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:35 AM | 7:25 AM | 4h 50m | Daily | Greyhound Full timetable |
| 1:00 PM | 6:30 PM | 6h 30m | Daily | Greyhound Full timetable |
| 1:55 PM | 6:55 PM | 6h 00m | Daily | Greyhound Full timetable |
| 6:30 PM | 11:00 PM | 5h 30m | Daily | Greyhound Full timetable |
Route map
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Where to board in Louisville Where you get off in Manchester The route of the busiest trip
Where to catch the bus in Louisville
- Louisville Bus Station Map of Louisville Bus Station (Google Maps)
Where the bus stops in Manchester
- Manchester Shell Map of Manchester Shell (Google Maps)
Return trip: Manchester to Louisville
Questions
How long is the bus from Louisville to Manchester?
The fastest direct bus takes 4 hours 50 minutes; the typical trip is 6 hours.
What time is the first bus from Louisville to Manchester?
The earliest departure is at 3:35 AM (Daily) and the last at 6:30 PM (Daily).
Which bus companies go from Louisville to Manchester?
Greyhound runs direct buses on this route.
Where do I catch the bus in Louisville?
Buses to Manchester leave from Louisville Bus Station.