MO → MO · about 120 miles
Columbia to St. Louis bus schedule
Greyhound runs 14 direct buses a week from Columbia to St. Louis. The fastest takes 2 hours 50 minutes; the first bus leaves at 8:30 AM and the last at 8:05 PM.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 2h 50m
- First bus
- 8:30 AM
- Last bus
- 8:05 PM
Timetable
Every bus leaves from Columbia Wabash Station and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 8:30 AM | 12:05 PM | 3h 35m | Daily | Greyhound Full timetable |
| 8:05 PM | 10:55 PM | 2h 50m | Daily | Greyhound Full timetable |
Route map
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Where to board in Columbia Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Columbia
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Columbia
Questions
How long is the bus from Columbia to St. Louis?
The fastest direct bus takes 2 hours 50 minutes.
What time is the first bus from Columbia to St. Louis?
The earliest departure is at 8:30 AM (Daily) and the last at 8:05 PM (Daily).
Which bus companies go from Columbia to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Columbia?
Buses to St. Louis leave from Columbia Wabash Station.