OH → NY · about 306 miles
Cleveland to Syracuse bus & train schedule
Amtrak and Greyhound run 21 direct buses and trains a week from Cleveland to Syracuse. The fastest takes 5 hours 38 minutes; the first departure leaves at 4:30 AM and the last at 5:50 AM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 21
- Fastest trip
- 5h 38m
- First departure
- 4:30 AM
- Last departure
- 5:50 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 4:30 AM | 11:20 AM | 6h 50m | Daily | Cleveland Bus Station (Brook Park) to Syracuse Bus Station | Greyhound Full timetable |
| 5:50 AM | 11:28 AM | 5h 38m | Daily | Cleveland to Syracuse Regional Transportation Center | Amtrak Full timetable |
Route map
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Where to board in Cleveland Where you get off in Syracuse The route of the busiest trip
Where to board in Cleveland
Where buses and trains stop in Syracuse
Return trip: Syracuse to Cleveland
Questions
How long is the bus or train from Cleveland to Syracuse?
The fastest direct bus or train takes 5 hours 38 minutes; the typical trip is 5 hours 38 minutes.
What time is the first departure from Cleveland to Syracuse?
The earliest departure is at 4:30 AM (Daily) and the last at 5:50 AM (Daily).
Which bus and rail companies go from Cleveland to Syracuse?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in Cleveland?
Buses and trains to Syracuse leave from Cleveland Amtrak station and Cleveland (Brook Park).