NY → OH · about 306 miles
Syracuse to Cleveland bus & train schedule
Amtrak and Greyhound run 21 direct buses and trains a week from Syracuse to Cleveland. The fastest takes 5 hours 48 minutes; the first departure leaves at 7:35 PM and the last at 10:05 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 21
- Fastest trip
- 5h 48m
- First departure
- 7:35 PM
- Last departure
- 10:05 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 7:35 PM | 2:20 AM +1 day | 6h 45m | Daily | Syracuse Bus Station to Cleveland Bus Station (Brook Park) | Greyhound Full timetable |
| 10:05 PM | 3:53 AM +1 day | 5h 48m | Daily | Syracuse Regional Transportation Center to Cleveland | Amtrak Full timetable |
Route map
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Where to board in Syracuse Where you get off in Cleveland The route of the busiest trip
Where to board in Syracuse
Where buses and trains stop in Cleveland
Return trip: Cleveland to Syracuse
Questions
How long is the bus or train from Syracuse to Cleveland?
The fastest direct bus or train takes 5 hours 48 minutes; the typical trip is 5 hours 48 minutes.
What time is the first departure from Syracuse to Cleveland?
The earliest departure is at 7:35 PM (Daily) and the last at 10:05 PM (Daily).
Which bus and rail companies go from Syracuse to Cleveland?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in Syracuse?
Buses and trains to Cleveland leave from Syracuse Regional Transportation Center.