OH → MO · about 471 miles
Cambridge to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Cambridge to St. Louis. The fastest takes 10 hours 35 minutes; every bus leaves at 10:20 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 10h 35m
- Leaves at
- 10:20 PM
Timetable
Every bus leaves from Cambridge Marathon and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:20 PM | 7:55 AM +1 day | 10h 35m | Daily | Greyhound Full timetable |
Route map
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Where to board in Cambridge Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Cambridge
- Cambridge Marathon Map of Cambridge Marathon (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Cambridge
Questions
How long is the bus from Cambridge to St. Louis?
The fastest direct bus takes 10 hours 35 minutes.
What time is the first bus from Cambridge to St. Louis?
Every departure is at 10:20 PM (Daily).
Which bus companies go from Cambridge to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Cambridge?
Buses to St. Louis leave from Cambridge Marathon.