MO → OH · about 471 miles
St. Louis to Cambridge bus schedule
Greyhound runs 7 direct buses a week from St. Louis to Cambridge. The fastest takes 12 hours 25 minutes; every bus leaves at 2:00 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 12h 25m
- Leaves at
- 2:00 AM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Cambridge Marathon. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:00 AM | 3:25 PM | 12h 25m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Cambridge The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Cambridge
- Cambridge Marathon Map of Cambridge Marathon (Google Maps)
Return trip: Cambridge to St. Louis
Questions
How long is the bus from St. Louis to Cambridge?
The fastest direct bus takes 12 hours 25 minutes.
What time is the first bus from St. Louis to Cambridge?
Every departure is at 2:00 AM (Daily).
Which bus companies go from St. Louis to Cambridge?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Cambridge leave from St Louis Bus Station.