TX → MO · about 685 miles
Amarillo to St. Louis bus schedule
Greyhound runs 7 direct buses a week from Amarillo to St. Louis. The fastest takes 14 hours 25 minutes; the first bus leaves at 6:35 AM and the last at 4:40 PM.
Timetable data from · Schedule last changed
- Buses a week
- 7
- Fastest trip
- 14h 25m
- First bus
- 6:35 AM
- Last bus
- 4:40 PM
Timetable
Every bus leaves from Amarillo Multimodal Transfer Sta and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 6:35 AM | 10:45 PM | 16h 10m | Daily | Greyhound Full timetable |
| 4:40 PM New | 7:05 AM +1 day | 14h 25m | Daily from Nov 3 | Greyhound Full timetable |
Route map
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Where to board in Amarillo Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Amarillo
- Amarillo Multimodal Transfer Sta Map of Amarillo Multimodal Transfer Sta (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Amarillo
Questions
How long is the bus from Amarillo to St. Louis?
The fastest direct bus takes 14 hours 25 minutes.
What time is the first bus from Amarillo to St. Louis?
The earliest departure is at 6:35 AM (Daily) and the last at 4:40 PM (Daily).
Which bus companies go from Amarillo to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Amarillo?
Buses to St. Louis leave from Amarillo Multimodal Transfer Sta.