MO → TX · about 685 miles
St. Louis to Amarillo bus schedule
Greyhound runs 14 direct buses a week from St. Louis to Amarillo. The fastest takes 15 hours; the first bus leaves at 1:20 AM and the last at 8:40 AM.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 15h 00m
- First bus
- 1:20 AM
- Last bus
- 8:40 AM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Amarillo Multimodal Transfer Sta. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:20 AM | 4:30 PM | 15h 10m | Daily | Greyhound Full timetable |
| 8:40 AM New | 11:40 PM | 15h 00m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Amarillo The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Amarillo
- Amarillo Multimodal Transfer Sta Map of Amarillo Multimodal Transfer Sta (Google Maps)
Return trip: Amarillo to St. Louis
Questions
How long is the bus from St. Louis to Amarillo?
The fastest direct bus takes 15 hours.
What time is the first bus from St. Louis to Amarillo?
The earliest departure is at 1:20 AM (Daily) and the last at 8:40 AM (Daily).
Which bus companies go from St. Louis to Amarillo?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Amarillo leave from St Louis Bus Station.