DE → SC · about 445 miles
Wilmington to Florence train schedule
Amtrak runs 14 direct trains a week from Wilmington to Florence. The fastest takes 10 hours 26 minutes; the first train leaves at 7:55 AM and the last at 4:44 PM.
Timetable data from · No schedule changes since at least
- Trains a week
- 14
- Fastest trip
- 10h 26m
- First train
- 7:55 AM
- Last train
- 4:44 PM
Timetable
Every train leaves from Wilmington and arrives at Florence Amtrak Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 7:55 AM | 8:43 PM | 12h 48m | Daily | Amtrak Full timetable |
| 4:42 PM | 3:10 AM +1 day | 10h 28m | Daily | Amtrak Full timetable |
| 4:44 PM | 3:10 AM +1 day | 10h 26m | Daily from Dec 19 | Amtrak Full timetable |
Route map
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Where to board in Wilmington Where you get off in Florence The route of the busiest trip
Where to catch the train in Wilmington
Where the train stops in Florence
Return trip: Florence to Wilmington
Questions
How long is the train from Wilmington to Florence?
The fastest direct train takes 10 hours 26 minutes; the typical trip is 12 hours 48 minutes.
What time is the first train from Wilmington to Florence?
The earliest departure is at 7:55 AM (Daily) and the last at 4:44 PM (Daily).
Which rail companies go from Wilmington to Florence?
Amtrak runs direct trains on this route.
Where do I catch the train in Wilmington?
Trains to Florence leave from Wilmington E Front St.