NY → SC · about 552 miles
New York to Florence bus & train schedule
Amtrak and FlixBus run 19 direct buses and trains a week from New York to Florence. The fastest takes 12 hours 40 minutes; the first departure leaves at 6:02 AM and the last at 4:30 PM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 19
- Fastest trip
- 12h 40m
- First departure
- 6:02 AM
- Last departure
- 4:30 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:02 AM | 8:43 PM | 14h 41m | Daily | Ny Moynihan Train Hall At Penn Station to Florence Amtrak Station | Amtrak Full timetable |
| 2:30 PM | 3:10 AM +1 day | 12h 40m | Daily | Ny Moynihan Train Hall At Penn Station to Florence Amtrak Station | Amtrak Full timetable |
| 4:30 PM | 5:45 AM +1 day | 13h 15m | Wed–Sun | NYC Chinatown 28 Allen St to Florence Sc | FlixBus Full timetable |
Route map
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Where to board in New York Where you get off in Florence The route of the busiest trip
Where to board in New York
Where buses and trains stop in Florence
Return trip: Florence to New York
Questions
How long is the bus or train from New York to Florence?
The fastest direct bus or train takes 12 hours 40 minutes; the typical trip is 13 hours 15 minutes.
What time is the first departure from New York to Florence?
The earliest departure is at 6:02 AM (Daily) and the last at 4:30 PM (Wed–Sun).
Which bus and rail companies go from New York to Florence?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in New York?
Buses and trains to Florence leave from Ny Moynihan Train Hall At Penn Station and NYC Chinatown 28 Allen St.