IA → IA · about 88 miles
Waterloo to Des Moines bus schedule
Greyhound runs 5 direct buses a week from Waterloo to Des Moines. The fastest takes 2 hours 55 minutes; every bus leaves at 3:50 PM.
Timetable data from · Schedule last changed
- Buses a week
- 5
- Fastest trip
- 2h 55m
- Leaves at
- 3:50 PM
Timetable
Every bus leaves from Waterloo Union Bus Depot and arrives at Des Moines. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:50 PM | 6:45 PM | 2h 55m | Wed–Sun | Greyhound Full timetable |
Route map
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Where to board in Waterloo Where you get off in Des Moines The route of the busiest trip
Where to catch the bus in Waterloo
- Waterloo Union Bus Depot Map of Waterloo Union Bus Depot (Google Maps)
Where the bus stops in Des Moines
- Des Moines bus stop Map of Des Moines bus stop (Google Maps)
Return trip: Des Moines to Waterloo
Questions
How long is the bus from Waterloo to Des Moines?
The fastest direct bus takes 2 hours 55 minutes.
What time is the first bus from Waterloo to Des Moines?
Every departure is at 3:50 PM (Wed–Sun).
Which bus companies go from Waterloo to Des Moines?
Greyhound runs direct buses on this route.
Where do I catch the bus in Waterloo?
Buses to Des Moines leave from Waterloo Union Bus Depot.