TX → MO · about 790 miles
San Antonio to St. Louis train schedule
Amtrak runs 10 direct trains a week from San Antonio to St. Louis. The fastest takes 24 hours 42 minutes; every train leaves at 6:48 AM.
Timetable data from · No schedule changes since at least
- Trains a week
- 10
- Fastest trip
- 24h 42m
- Leaves at
- 6:48 AM
Timetable
Every train leaves from San Antonio Amtrak Station and arrives at St. Louis. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 6:48 AM | 7:30 AM +1 day | 24h 42m | Daily | Amtrak Full timetable |
Route map
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Where to board in San Antonio Where you get off in St. Louis The route of the busiest trip
Where to catch the train in San Antonio
Where the train stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to San Antonio
Questions
How long is the train from San Antonio to St. Louis?
The fastest direct train takes 24 hours 42 minutes; the typical trip is 24 hours 42 minutes.
What time is the first train from San Antonio to St. Louis?
Every departure is at 6:48 AM (Daily).
Which rail companies go from San Antonio to St. Louis?
Amtrak runs direct trains on this route.
Where do I catch the train in San Antonio?
Trains to St. Louis leave from San Antonio Amtrak Station.