MO → MO · about 130 miles
Poplar Bluff to St. Louis train schedule
Amtrak runs 10 direct trains a week from Poplar Bluff to St. Louis. The fastest takes 4 hours 41 minutes; every train leaves at 2:49 AM.
Timetable data from · No schedule changes since at least
- Trains a week
- 10
- Fastest trip
- 4h 41m
- Leaves at
- 2:49 AM
Timetable
Every train leaves from Poplar Bluff Amtrak Station and arrives at St. Louis. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 2:49 AM | 7:30 AM | 4h 41m | Daily | Amtrak Full timetable |
Route map
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Where to board in Poplar Bluff Where you get off in St. Louis The route of the busiest trip
Where to catch the train in Poplar Bluff
- Poplar Bluff Amtrak Station Map of Poplar Bluff Amtrak Station (Google Maps)
Where the train stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Poplar Bluff
Questions
How long is the train from Poplar Bluff to St. Louis?
The fastest direct train takes 4 hours 41 minutes; the typical trip is 4 hours 41 minutes.
What time is the first train from Poplar Bluff to St. Louis?
Every departure is at 2:49 AM (Daily).
Which rail companies go from Poplar Bluff to St. Louis?
Amtrak runs direct trains on this route.
Where do I catch the train in Poplar Bluff?
Trains to St. Louis leave from Poplar Bluff Amtrak Station.