MO → IL · about 382 miles
Poplar Bluff to Chicago train schedule
Amtrak runs 10 direct trains a week from Poplar Bluff to Chicago. The fastest takes 11 hours; every train leaves at 2:49 AM.
Timetable data from · No schedule changes since at least
- Trains a week
- 10
- Fastest trip
- 11h 00m
- Leaves at
- 2:49 AM
Timetable
Every train leaves from Poplar Bluff Amtrak Station and arrives at Chicago Union Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 2:49 AM | 1:49 PM | 11h 00m | Daily | Amtrak Full timetable |
Route map
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Where to board in Poplar Bluff Where you get off in Chicago The route of the busiest trip
Where to catch the train in Poplar Bluff
- Poplar Bluff Amtrak Station Map of Poplar Bluff Amtrak Station (Google Maps)
Where the train stops in Chicago
Return trip: Chicago to Poplar Bluff
Questions
How long is the train from Poplar Bluff to Chicago?
The fastest direct train takes 11 hours; the typical trip is 11 hours.
What time is the first train from Poplar Bluff to Chicago?
Every departure is at 2:49 AM (Daily).
Which rail companies go from Poplar Bluff to Chicago?
Amtrak runs direct trains on this route.
Where do I catch the train in Poplar Bluff?
Trains to Chicago leave from Poplar Bluff Amtrak Station.