PA → IL · about 411 miles
Pittsburgh to Chicago bus & train schedule
Amtrak, FlixBus and Greyhound run 20 direct buses and trains a week from Pittsburgh to Chicago. The fastest takes 9 hours 46 minutes; the first departure leaves at 8:35 AM and the last at 11:59 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 20
- Fastest trip
- 9h 46m
- First departure
- 8:35 AM
- Last departure
- 11:59 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 8:35 AM | 8:05 PM | 12h 30m | Daily | Pittsburgh PA - Bus Station (PGB) to Chicago Bus Station | Greyhound Full timetable |
| 7:45 PM | 5:40 AM +1 day | 10h 55m | Daily except Tue | Pittsburgh PA - Bus Station (PGB) to Chicago 95th / Dan Ryan | FlixBus Full timetable |
| 11:59 PM | 8:45 AM +1 day | 9h 46m | Daily | Pittsburgh Amtrak Station to Chicago Union Station | Amtrak Full timetable |
| 11:59 PM | 9:45 AM +1 day | 10h 46m | Sun | Pittsburgh Amtrak Station to Chicago Union Station | Amtrak Full timetable |
Route map
The map needs JavaScript.
Where to board in Pittsburgh Where you get off in Chicago The route of the busiest trip
Where to board in Pittsburgh
Where buses and trains stop in Chicago
Return trip: Chicago to Pittsburgh
Questions
How long is the bus or train from Pittsburgh to Chicago?
The fastest direct bus or train takes 9 hours 46 minutes; the typical trip is 10 hours 46 minutes.
What time is the first departure from Pittsburgh to Chicago?
The earliest departure is at 8:35 AM (Daily) and the last at 11:59 PM (Sun).
Which bus and rail companies go from Pittsburgh to Chicago?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Pittsburgh?
Buses and trains to Chicago leave from Pittsburgh Amtrak Station and Pittsburgh PA - Bus Station (PGB).