IL → PA · about 411 miles
Chicago to Pittsburgh bus & train schedule
Amtrak, FlixBus and Greyhound run 31 direct buses and trains a week from Chicago to Pittsburgh. The fastest takes 9 hours 25 minutes; the first departure leaves at 6:30 AM and the last at 7:15 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 31
- Fastest trip
- 9h 25m
- First departure
- 6:30 AM
- Last departure
- 7:15 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:30 AM | 6:05 PM | 10h 35m | Daily | Chicago Bus Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 7:00 AM | 8:50 PM | 12h 50m | Mon, Fri, Sat, Sun | Chicago Bus Station to Pittsburgh PA - Bus Station (PGB) | FlixBus Full timetable |
| 5:35 PM New | 5:05 AM +1 day | 10h 30m | Sun | Chicago Union Station to Pittsburgh Amtrak Station | Amtrak Full timetable |
| 6:00 PM | 5:25 AM +1 day | 10h 25m | Daily | Chicago Bus Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 6:40 PM | 5:05 AM +1 day | 9h 25m | Daily | Chicago Union Station to Pittsburgh Amtrak Station | Amtrak Full timetable |
| 7:15 PM | 7:15 AM +1 day | 11h 00m | Daily except Tue | Chicago Bus Station to Pittsburgh PA - Bus Station (PGB) | FlixBus Full timetable |
Route map
The map needs JavaScript.
Where to board in Chicago Where you get off in Pittsburgh The route of the busiest trip
Where to board in Chicago
Where buses and trains stop in Pittsburgh
Return trip: Pittsburgh to Chicago
Questions
How long is the bus or train from Chicago to Pittsburgh?
The fastest direct bus or train takes 9 hours 25 minutes; the typical trip is 10 hours 30 minutes.
What time is the first departure from Chicago to Pittsburgh?
The earliest departure is at 6:30 AM (Daily) and the last at 7:15 PM (Daily except Tue).
Which bus and rail companies go from Chicago to Pittsburgh?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Chicago?
Buses and trains to Pittsburgh leave from Chicago Union Station and Chicago Bus Station.