PA → PA · about 166 miles
Harrisburg to Pittsburgh bus & train schedule
Amtrak, Greyhound and OurBus run 51 direct buses and trains a week from Harrisburg to Pittsburgh. The fastest takes 3 hours 45 minutes; the first departure leaves at 2:30 AM and the last at 8:05 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 51
- Fastest trip
- 3h 45m
- First departure
- 2:30 AM
- Last departure
- 8:05 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 2:30 AM | 6:30 AM | 4h 00m | Daily | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 9:39 AM New | 3:14 PM | 5h 35m | Daily from Nov 18 | Harrisburg to Pittsburgh Amtrak Station | Amtrak Full timetable |
| 11:25 AM | 6:10 PM | 6h 45m | Daily | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 12:30 PM | 4:30 PM | 4h 00m | Sun from Nov 29 | Harrisburg, PA (326 Chestnut Street btwn. South 4th & Dewberry in front of bus shelter, west side of block, across from train station driveway) to Pittsburgh, PA (Carnegie Mellon area- Bus stop at the intersection of Forbes Ave and Morewood, opposite to Carnegie Mellon University Alumni House) | OurBus Full timetable |
| 1:40 PM | 5:25 PM | 3h 45m | Thu–Sun | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 2:30 PM | 6:25 PM | 3h 55m | Sun from Nov 29 | Harrisburg, PA (326 Chestnut Street btwn. South 4th & Dewberry in front of bus shelter, west side of block, across from train station driveway) to Pittsburgh, PA (Carnegie Mellon area- Bus stop at the intersection of Forbes Ave and Morewood, opposite to Carnegie Mellon University Alumni House) | OurBus Full timetable |
| 2:36 PM | 8:05 PM | 5h 29m | Daily | Harrisburg to Pittsburgh Amtrak Station | Amtrak Full timetable |
| 2:50 PM | 7:00 PM | 4h 10m | Daily | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 4:25 PM New | 9:54 PM | 5h 29m | Daily from Nov 18 | Harrisburg to Pittsburgh Amtrak Station | Amtrak Full timetable |
| 5:30 PM | 10:20 PM | 4h 50m | Wed–Sun | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 7:50 PM | 11:59 PM | 4h 09m | Daily | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
| 8:05 PM | 12:05 AM +1 day | 4h 00m | Daily | Harrisburg Market St Train Station to Pittsburgh PA - Bus Station (PGB) | Greyhound Full timetable |
Route map
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Where to board in Harrisburg Where you get off in Pittsburgh The route of the busiest trip
Where to board in Harrisburg
Where buses and trains stop in Pittsburgh
Return trip: Pittsburgh to Harrisburg
Questions
How long is the bus or train from Harrisburg to Pittsburgh?
The fastest direct bus or train takes 3 hours 45 minutes; the typical trip is 4 hours 10 minutes.
What time is the first departure from Harrisburg to Pittsburgh?
The earliest departure is at 2:30 AM (Daily) and the last at 8:05 PM (Daily).
Which bus and rail companies go from Harrisburg to Pittsburgh?
Amtrak, Greyhound and OurBus run direct buses and trains on this route.
Where do I board in Harrisburg?
Buses and trains to Pittsburgh leave from Harrisburg Market St Train Station and Harrisburg (326 Chestnut Street btwn).