IL → MO · about 71 miles
Mount Vernon to St. Louis bus schedule
Greyhound runs 14 direct buses a week from Mount Vernon to St. Louis. The fastest takes 1 hour 20 minutes; the first bus leaves at 2:30 PM and the last at 8:10 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 1h 20m
- First bus
- 2:30 PM
- Last bus
- 8:10 PM
Timetable
Every bus leaves from Mt. Vernon IL (MVI) and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:30 PM | 3:55 PM | 1h 25m | Daily | Greyhound Full timetable |
| 8:10 PM | 9:30 PM | 1h 20m | Daily | Greyhound Full timetable |
Route map
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Where to board in Mount Vernon Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Mount Vernon
- Mt. Vernon IL (MVI) Map of Mt. Vernon IL (MVI) (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Mount Vernon
Questions
How long is the bus from Mount Vernon to St. Louis?
The fastest direct bus takes 1 hour 20 minutes.
What time is the first bus from Mount Vernon to St. Louis?
The earliest departure is at 2:30 PM (Daily) and the last at 8:10 PM (Daily).
Which bus companies go from Mount Vernon to St. Louis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Mount Vernon?
Buses to St. Louis leave from Mt. Vernon IL (MVI).