MN → WI · about 124 miles
Minneapolis to La Crosse bus schedule
Jefferson Lines runs 9 direct buses a week from Minneapolis to La Crosse. The fastest takes 3 hours 50 minutes; the first bus leaves at 10:45 AM and the last at 2:00 PM. The standard fare is $29 one way.
Timetable data from · No schedule changes since at least
- Buses a week
- 9
- Fastest trip
- 3h 50m
- First bus
- 10:45 AM
- Last bus
- 2:00 PM
- Standard fare
- $29
A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.
Timetable
Every bus leaves from Minneapolis and arrives at La Crosse. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company | Ticket |
|---|---|---|---|---|---|
| 10:45 AM | 2:35 PM | 3h 50m | Daily | Jefferson Lines Full timetable | Book (carrier website) |
| 2:00 PM | 6:25 PM | 4h 25m | Thu, Sun | Jefferson Lines Full timetable | Book (carrier website) |
Route map
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Where to board in Minneapolis Where you get off in La Crosse The route of the busiest trip
Where to catch the bus in Minneapolis
Where the bus stops in La Crosse
Return trip: La Crosse to Minneapolis
Questions
How long is the bus from Minneapolis to La Crosse?
The fastest direct bus takes 3 hours 50 minutes.
How much is the bus from Minneapolis to La Crosse?
The standard one-way fare with Jefferson Lines is $29. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.
What time is the first bus from Minneapolis to La Crosse?
The earliest departure is at 10:45 AM (Daily) and the last at 2:00 PM (Thu, Sun).
Which bus companies go from Minneapolis to La Crosse?
Jefferson Lines runs direct buses on this route.
Where do I catch the bus in Minneapolis?
Buses to La Crosse leave from Minneapolis (Bus Station).