WI → MN · about 124 miles

La Crosse to Minneapolis bus schedule

Jefferson Lines runs 9 direct buses a week from La Crosse to Minneapolis. The fastest takes 3 hours 10 minutes; the first bus leaves at 1:10 PM and the last at 4:15 PM. The standard fare is $29 one way.

Timetable data from · No schedule changes since at least

Buses a week
9
Fastest trip
3h 10m
First bus
1:10 PM
Last bus
4:15 PM
Standard fare
$29

A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.

Timetable

Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.

Direct buses from La Crosse, WI to Minneapolis, MN
DepartsArrivesDurationDaysStopsBus companyTicket
1:10 PM5:25 PM4h 15mDailyLa Crosse (U of WI) to Minneapolis (U of MN - Huron Blvd)Jefferson Lines
Full timetable
Book (carrier website)
4:15 PM7:25 PM3h 10mMon, FriLa Crosse (U of WI) to Minneapolis (Mall of America)Jefferson Lines
Full timetable
Book (carrier website)

Route map

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Where to board in La Crosse Where you get off in Minneapolis The route of the busiest trip

Return trip: Minneapolis to La Crosse

Questions

How long is the bus from La Crosse to Minneapolis?

The fastest direct bus takes 3 hours 10 minutes.

How much is the bus from La Crosse to Minneapolis?

The standard one-way fare with Jefferson Lines is $29. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees.

What time is the first bus from La Crosse to Minneapolis?

The earliest departure is at 1:10 PM (Daily) and the last at 4:15 PM (Mon, Fri).

Which bus companies go from La Crosse to Minneapolis?

Jefferson Lines runs direct buses on this route.

Where do I catch the bus in La Crosse?

Buses to Minneapolis leave from La Crosse (U of WI).